- Main article: Zombie DNA
The Zombie virus has once again evolved to introduce different characteristics. By applying the desired "DNA point" to different skill sets, players are able to improve the performance of the zombies. The application is universal across all zombies.
Two new special zombie types: Metatronic and Lilith have been added. They have a chance to be chosen randomly if the player opts for the random selecting option in Zombie 3: Hero. Unlike other zombies however, they are not enhanceable.
- The Z-Noid Chinese trailer shows the view model of a Regular zombie.